Smoking Cessation Web Study: Tomando Control

This project of the University of California, San Francisco/San Francisco General Hospital Latino Mental Health Research Program is being conducted in collaboration with the University of California, San Francisco Medical Effectiveness Research Center for Diverse Populations (MERC) and the University of California, San Diego.

The Tobacco Related Disease Research Program funded the establishment of the Spanish/English Web Site for Smoking Cessation Trials at and

Phase 1

During Phase I of the study, we created the basic site and tested its ability to: 

  1. Recruit participants
  2. Obtain informed consent
  3. Obtain initial assessment data
  4. Provide one intervention
  5. Obtain follow-up data, all with minimal human intervention. We recruited over 4500 smokers, of whom over 1000 were Spanish-speaking

Phase 2

During Phase II we carried out three sets of studies comparing two smoking cessation conditions to each other.

Publications from the first two phases include:

  • Lenert L, Muñoz RF, Stoddard J, Delucchi K, Bansond A, Skoczen S, Perez-Stable EJ (2003). Design and pilot evaluation of an internet smoking cessation program. J Am Med Inform Assoc .; 10(1):16-20.
  • Lenert L, Muñoz RF, Perez JE, Bansod A (2004).   Automated e-mail messaging as a tool for improving quit rates in an internet smoking cessation intervention. J Am Med Inform Assoc.; 11(4):235-40. Epub 2004 Apr 2.
  • Stoddard J, Delucchi K, Muñoz R, Collins N, Pérez-Stable EJ, Augustson E, Lenert L (2005).  Smoking cessation research via the internet: a feasibility study. J Health Commun.; 10(1):27-41.
  • Muñoz RF, Lenert LL , Delucchi K, Stoddard J, Pérez JE, Penilla C, Pérez-Stable EJ (2006 ).Toward evidence-based Internet interventions: A Spanish/English Web site for international smoking cessation trials. Nicotine & Tobacco Research, 8. 77-87.

Funding Sources

Tobacco-Related Disease Research Program Grant # 10RT-0326

“Spanish/English web site for smoking cessation trials.”

Principal Investigator: Ricardo F. Muñoz, Ph.D.


Leslie Lenert, M.D.,

Eliseo J. Pérez-Stable, M.D.,

Kevin Delucchi, Ph.D.

Phase 3

During Phase III, we compared four methods to stop smoking via the Web in a randomized control trial.

Publications from this phase include:

  • Muñoz RF, Barrera AZ, Delucchi K, Penilla C, Torres LD, Pérez-Stable EJ. International Spanish/English Internet smoking cessation trial yields 20% abstinence rates at 1 year. Nicotine Tob Res. 2009 Sep;11(9):1025-34. Epub 2009 Jul 29.
  • Torres LD, Barrera AZ, Delucchi K, Penilla C, Pérez-Stable EJ, Muñoz RF. Quitting smoking does not increase the risk of major depressive episodes among users of Internet smoking cessation interventions. Psychol Med. 2009 Jul 23;:1-9 [Epub ahead of print]
  • Barrera AZ, Pérez-Stable EJ, Delucchi KL, Muñoz RF. Global reach of an Internet smoking cessation intervention among Spanish- and English- speaking smokers from 157 countries. Int J Environ Res Public Health.  2009 Mar;6(3):927-40. Epub 2009 Feb 26.